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Pharmaceutical Organic Chemistry-II Book B.Pharm 3rd Sem

Pharmaceutical Organic Chemistry-II Book B.Pharm 3rd Sem

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B.Pharm.,Third Semester
According to the syllabus based on ‘Pharmacy Council of India’
Syllabus
Module 01                                                                                                                           10 Hours
Benzene and Its Derivatives
Analytical, synthetic and other evidences in the derivation of structure of benzene, Orbital picture, resonance in benzene, aromatic characters, Huckel’s rule.
Reactions of benzene - nitration, sulphonation, halogenation- reactivity, Friedelcrafts alkylation- reactivity, limitations, Friedelcrafts acylation.
Substituents, effect of substituents on reactivity and orientation of mono substituted benzene compounds towards electrophilic substitution reaction.
Structure and uses of DDT, Saccharin, BHC and Chloramine.
 
Module 02                                                                                                                           10 Hours
Phenols*
Acidity of phenols, effect of substituents on acidity, qualitative tests, Structure and uses
of phenol, cresols, resorcinol, naphthols.
Aromatic Amines*
Basicity of amines, effect of substituents on basicity, and synthetic uses of aryl
diazonium salts
Aromatic Acids*
Acidity, effect of substituents on acidity and important reactions of benzoic acid.
 
Module 03                                                                                                                           10 Hours
Fats and Oils
Fatty acids – reactions.
Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying oils.
Analytical constants – Acid value, Saponification value, Ester value, Iodine value, Acetyl value, Reichert Meissl (RM) value – significance and principle involved in their determination.
 
Module 04                                                                                                                           08 Hours
Polynuclear Hydrocarbons
Synthesis, reactions.
Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene, Diphenylmethane, Triphenylmethane and their derivatives.
 
Module 05                                                                                                                           07 Hours
Cycloalkanes*
Stabilities – Baeyer’s strain theory, limitation of Baeyer’s strain theory, Coulson and
Moffitt’s modification, Sachse Mohr’s theory (Theory of strainless rings), reactions of
cyclopropane and cyclobutane only.
 


 

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