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Chapter
|
Topic
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Hours
|
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1)
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Introduction to Biochemistry: Scope of biochemistry in pharmacy; Cell and its biochemical organization.
|
2
|
|
2)
|
Carbohydrates
-
Definition, classification with examples, chemical
properties
-
Monosaccharides - Structure of glucose, fructose, and
galactose
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Disaccharides - structure of maltose, lactose, and sucrose
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Polysaccharides - chemical nature of starch and glycogen
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Qualitative tests and biological role of carbohydrates
|
5
|
|
3)
|
Proteins
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Definition, classification of proteins based on
-
composition and solubility with examples
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Definition, classification of amino acids based on
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Chemical nature and nutritional requirements withexamples
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Structure of proteins (four levels of organization of protein structure)
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Qualitative tests and biological role of proteins and amino acids
-
Diseases related to malnutrition of proteins.
|
5
|
|
4)
|
Lipids
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Definition, classification with examples
-
Structure and properties of triglycerides (oils and fats)
-
Fatty acid classification - Based onchemical and nutritional requirements with examples
-
Structure and functions of cholesterol in the body
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Lipoproteins - types, composition and functions in the body
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Qualitative tests and functions of lipids
|
5
|
|
5)
|
Nucleic Acids
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Definition, purine and pyrimidine bases
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Components of nucleosides and nucleotides with examples
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Structure of DNA (Watson and Crick model), RNA and
-
their functions
|
4
|
|
6)
|
Enzymes
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Definition, properties and IUB and MB classification
-
Factors affecting enzyme activity
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Mechanism of action of enzymes, Enzyme inhibitors
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Therapeutic and pharmaceutical importance of enzymes
|
5
|
|
7)
|
Vitamins
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Definition and classification with examples
-
Sources, chemical nature, functions, coenzyme form, recommended dietary requirements, deficiency diseases of fat-and water-soluble vitamins
|
6
|
|
8)
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Metabolism (Study of cycle/pathways without chemical structures)
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Metabolism of Carbohydrates: Glycolysis, TCA cycle and glycogen metabolism, regulation of blood glucose level. Diseases related to abnormal metabolism of Carbohydrates
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Metabolism of lipids: Lipolysis, β-oxidation of Fatty acid (Palmitic acid) ketogenesis and ketolysis. Diseases related to abnormal metabolism of lipids such as Ketoacidosis, Fatty liver, Hypercholesterolemia
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Metabolism of Amino acids (Proteins): General reactions of amino acids and its significance– Transamination, deamination, Urea cycle and decarboxylation. Diseases related to abnormal metabolism of amino acids, Disorders of ammonia metabolism, phenylketonuria, alkaptonuria and Jaundice.
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Biological oxidation: Electron transport chain and Oxidative phosphorylation
|
20
|
|
9)
|
Minerals: Types, Functions, Deficiency diseases, recommended dietary requirements
|
05
|
|
10)
|
Water and Electrolytes
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Distribution, functions of water in the body
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Water turnover and balance
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Electrolyte composition of the body fluids, Dietary intake of electrolyte and Electrolyte balance
-
Dehydration, causes of dehydration and oral rehydration therapy
|
05
|
|
11)
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Introduction to Biotechnology
|
01
|
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12)
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Organ Function Tests
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Functions of kidney and routinely performed tests to assess the functions of kidney and their clinical significances
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Functions of liver and routinely performed tests to assess the functions of liver and their clinical significances
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Lipid profile tests and its clinical significances
|
06
|
|
13)
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Introduction to Pathology of Blood and Urine
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Lymphocytes and Platelets, their role in health and disease
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Erythrocytes - Abnormal cells and their significance
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Normal and Abnormal constituents of Urine and their significance
|
06
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